However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. A Mayo Clinic study published this month in Pacing and Electrophysiology (PACE), suggests that a class of medications more commonly prescribed for older adults is a strong first-line treatment for teenagers with a debilitating condition called postural orthostatic tachycardia syndrome, or POTS. Its a place where people with certain conditions can find support and connect with others. Examples of statin drugs include atorvastatin (Lipitor) and simvastatin (Zocor). Your doctor will determine the best dosage to fit your needs. Zetia is sometimes used with medications in the statin drug class. Statins are cholesterol drugs that may be taken with Zetia. These problems can include muscle pain and muscle weakness, and rarely, muscle breakdown. Zetia is approved to treat certain forms of high cholesterol in children ages 10 years and older when used with a low-cholesterol diet. The effect of Zetia, atorvastatin, or simvastatin on other types of cholesterol levels in this study isnt known. (A drug class is a group of medications that work in a similar way.) Chylomicrons help your body, low-density lipoproteins (LDL), sometimes referred to as bad cholesterol, high-density lipoproteins (HDL), sometimes referred to as good cholesterol, triglycerides, which are a type of fat that are building blocks of cholesterol, Apo B (high levels of this protein are a sign of high cholesterol), non-HDL cholesterol (calculated by subtracting your HDL cholesterol level from your total cholesterol), were reduced by an average of 13% to 14% in people who used Zetia, ranged from not changing to being reduced by an average of 1% in people who used a placebo, were reduced by an average of 18% in people who used Zetia, increased by an average of 1% in people who used a placebo, decreased by an average of 13% to 14% in people who used Zetia alone, decreased by an average of 15% to 40% in people who used a statin alone, depending on the statin used, decreased by an average of 24% to 46% in people who used Zetia and a statin, depending on the statin used, ranged from decreasing by an average to 1% to increasing by an average of 4% in people who took a placebo, decreased by an average of 19% to 20% in people who used Zetia alone, decreased by an average of 20% to 54% in people who used a statin alone, depending on the statin used, decreased by an average of 34% to 61% in people who used Zetia and a statin, depending on the statin used. Theyll guide you with suggestions they may have to relieve these side effects. These symptoms can be signs of an infection. And your doctor can use this information to adjust your treatment plan if needed. Then theyll monitor whether the drug is working for you and whether you experience any side effects. Energy Drinks, such as Red Bull, should be avoided in those with POTS. Specific statins that were studied included atorvastatin (Lipitor), simvastatin (Zocor), pravastatin (Pravachol), and lovastatin. Zetia does not cause an increase or a decrease in blood pressure. To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine). Zetias effect on cardiovascular morbidity and mortality isnt known. Talk with your doctor to learn more about which medications are right for you. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. For this purpose, Zetia may be used alone or with fenofibrate. Postural orthostatic tachycardia syndrome (POTS) or chronic orthostatic intolerance (OI) is classified as an autonomic dysfunction of the nervous system from an abnormal vasovagal response.. Muscle problems are common side effects of statin drugs. What foods should I avoid while taking Zetia. . If your muscle-related side effects dont go away or become severe, tell your doctor right away. Twelve weeks of treatment with Zetia and atorvastatin or simvastatin was compared with atorvastatin or simvastatin used alone. These drugs havent been directly compared in clinical studies. diarrhea*. Uses. It isnt known how often this side effect occurred with Zetia in clinical studies. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. Other drugs are available that can treat your conditions. Side effects may be more likely in older adults. * For more information about this side effect, see " Zetia: Side effects explained " below. The following information is provided for clinicians and other healthcare professionals. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. As patients we need to be constantly wary because it is increasingly clear that the pharmas have abrogated their responsibility on our behalf. They may have suggestions depending on your weight and health goals. Symptoms of atherosclerosis may include confusion, fatigue (lack of energy), trouble breathing, or pain in your chest, arms, or legs. You should store Zetia tablets at a room temperature of 77F (25C) in a tightly sealed container away from light. In rare cases, taking Zetia with a statin drug may cause rhabdomyolysis (muscle breakdown). Its also not known if the drug is safe to take while breastfeeding or whether the drug passes into breast milk. If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. If youre currently taking cyclosporine, talk with your doctor about whether its safe for you to take Zetia. Zetia is FDA-approved to lower your total cholesterol level, and triglycerides are one part of your total cholesterol level. If your doctor has prescribed Zetia and youre interested in using ezetimibe instead, talk with your doctor. Statins lower cholesterol by preventing your liver from making new cholesterol. And talk with your doctor if you have any questions about eating certain foods with Zetia. Here are answers to some frequently asked questions about Zetia. If left untreated, it can cause your kidneys to stop working properly. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. The Food and Drug Administration (FDA) approves prescription drugs such as Zetia to treat certain conditions. Symptoms: This section is currently in development. Yes, treatment with Zetia should lower your triglycerides. If you have a history of heavy alcohol use and are taking Zetia with a statin drug, you may have a higher risk of side effects. What Are the Injectable Alternatives to Statins? Zetia comes as a tablet that you swallow. The expiration date helps guarantee that the medication is effective during this time. The autonomic nervous system is in charge of all bodily functions that we don't have to think about, such as: The sympathetic nervous system is part of the autonomic nervous system. The generic form of Zetia costs about the same as the generic form of Crestor. But in studies, some people had to stop taking the drug due to feeling dizzy. High cholesterol occurs when you have more cholesterol in your blood than your body needs. If you have high cholesterol with hypertension (high blood pressure) or diabetes, youll likely have to take other drugs with Zetia to treat these conditions. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Crestor, or with both drugs (when taken individually). The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Typical symptoms of POTS include: heart palpitations (feeling your heart beating or racing) dizziness or lightheadedness. 22% in people who used Zetia with fenofibrate, 20% in people who used Zetia with fenofibrate, people who used Zetia with atorvastatin or simvastatin had their LDL levels reduced by an average of 21% to 27% (the percentage varied depending on the dosage used), people who used atorvastatin or simvastatin alone had their LDL levels reduced by an average of 7%, people who used Zetia had their sitosterol levels decreased by an average of 21% and their campstrol levels decreased by an average of 24%, people who used a placebo had their sitosterol levels decreased by an average of 4% and their campstrol levels decreased by an average of 3%, bile acid sequestrants, such as cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), Both Zetia and Lipitor are FDA-approved to treat the following conditions* in adults when used with a. Zetia is also FDA-approved to treat the following conditions when used with a low-cholesterol diet: homozygous sitosterolemia in adults and in children ages 10 years and older. Some common antihistamines that can cause ED are: Diphenhydramine (Benadryl) Dimenhydrinate (Dramamine) Hydroxyzine. Crestor is available in a generic form called rosuvastatin. Your risk of developing serious side effects may increase if you take Zetia with other medications to treat high cholesterol, such as statin drugs. A medication timer may be useful, too. If you no longer need to take Zetia and have leftover medication, its important to dispose of it safely. Its not known if its safe to take Zetia while breastfeeding or if the drug passes into breast milk. And Zetia hasnt been shown to affect blood sugar levels in clinical studies of people with diabetes and people without diabetes. Recently, POTS has been diagnosed in some people who have had COVID-19. Physicians who treat dysautonomia can be located on our Physician List. Tramadol will usually cause a blistering type rash with itching which you do not describe. Learn about the drugs dosage, forms, strengths. You may not have any symptoms of gallstones unless they cause your gallbladder to swell. The generic is considered to be as safe and effective as the original drug. Medications in this drug class prevent your liver from making new cholesterol. Using Zetia for high cholesterol. However, if the side effects last longer than . Porphyrias have been associated with POTS symptoms (Stewart & Hensley, 1981). They can suggest ways to help relieve your side effects, or they may recommend a different treatment option for you. The symptoms develop immediately and include dizziness and an intense headache. Increasingly clear that the medication is effective during this time ( FDA ) approves drug. 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